Browsing by Author "Amalia, Fitri"

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    UJI AKTIVITAS ANTIJAMUR DARI EKSTRAK JAMUR ENDOFIT Botryosphaeria rhodina TERHADAP JAMUR Candida albicans
    (Elfitra, 2023-04) Amalia, Fitri; Hendra, Rudi; Haryani, Yuli
    Endophytic fungi are microorganisms that are able to form colonies in plant tissues without posing a threat to their hosts and that live in plant tissue systems at certain times. Botryosphaeria rhodina, isolated from mangroves in the Muara Sungai Siput region of the Bengkalis Regency, is one of the endophytic fungi with high biological activity. This study aims to isolate secondary metabolites from the extract of the endophytic fungus B. rhodina and assess their antifungal activity against Candida albicans. The microdilution method was used to determine the MIC (minimum inhibitory concentration) value, while the agar diffusion method was used to determine the MFC (minimum fungicidal concentration) value. Methanol and n-hexane extracts with concentrations of 1,000, 500 and 250 μg/mL were used as test samples. The results of the antifungal test revealed that the MIC values of the n-hexane extract, methanol extract, and MFC were 1,000 μg/mL, 500 μg/mL and 1,000 μg/mL, respectively, against C. albicans.