Browsing by Author "Tillah, M."

Now showing 1 - 1 of 1
  • No Thumbnail Available
    Item
    SINTESISDANUJITOKSISITASSENYAWAKALKON TURUNAN4’–METILASETOFENON
    (2014-03-27) Tillah, M.; Yuharmen; Zamri, A.
    (E)-3-(4-chlorophenyl)-1-p-tolylprop-2-en-1-one has been synthesized from 4’-methylacetophenoneand4 chlorobenzaldehydeusingNaOH(5%) asacatalystby Claisen Schmidt condensation in good yield.The product has been determined,interm of its melting point,identified byKLT,then elutedwithUV-Vis,FT-IR,MS,and 1H-NMR.Chalcones compound toxicity test was done using Brine Shrimp LethalityTest (BSLT)method against larvae Artemia salina Leach.LC50 value for compound(E)-3- (4-chlorophenyl)-1-p-tolylprop-2-en-1-one is 2,81 µg/mL. The analog chalcone compound are positively potential as anti-cancer.