SINTESIS DAN UJI TOKSISITAS SENYAWA 5-(4-KLOROFENIL)-3- (NAFTALEN-2-IL)-1-FENIL-1H-PIRAZOL DARI PIRAZOLIN

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dc.contributor.authorDewi, Gira Fitri
dc.contributor.supervisorJasril, Jasril
dc.date.accessioned2021-07-28T04:05:44Z
dc.date.available2021-07-28T04:05:44Z
dc.date.issued2020-08
dc.description.abstractPyrazole is a 5-ring heterocyclic compound which consist of 3 carbon atoms and 2 neighboring nitrogen atoms. This study was aimed to synthetized pyrazol compound and toxicity of the compound was determined by BSLT method. The pyrazole 5-(4- chlorophenyl)-3-(naphthalene-2-il)-phenyl-1H-pyrazole was synthesized through the oxidative aromatization reaction of pyrazolin compounds with glacial acetic acid. The synthesized compound was tested for purity using TLC, melting point and HPLC analysis. The structure of the synthesized compound was confirmed through UV spectroscopy and FTIR. The synthesis of pyrazole has the yield of 38,3%. Pyrazole was subjected to toxicity test through BSLT method using shrimp larvae (Artemia salina Leach). The pyrazole was toxic with LC50 value of 20,13 μg/mL.en_US
dc.description.sponsorshipJurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Riauen_US
dc.identifier.otherwahyu sari yeni
dc.identifier.urihttps://repository.unri.ac.id/handle/123456789/10054
dc.language.isoenen_US
dc.subjectaromatizationen_US
dc.subjectpyrazoleen_US
dc.subjectsynthesisen_US
dc.titleSINTESIS DAN UJI TOKSISITAS SENYAWA 5-(4-KLOROFENIL)-3- (NAFTALEN-2-IL)-1-FENIL-1H-PIRAZOL DARI PIRAZOLINen_US
dc.typeArticleen_US

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