PERBANDINGAN METODE SINTESIS ONE-POT SENYAWA 3-(3-BROMOFENIL)-5-(2-METOKSIFENIL)-1-FENIL-4,5- DIHIDRO-PIRAZOL

Simple item page
dc.contributor.authorIzzaty, Dini
dc.contributor.authorEryanti, Yum
dc.date.accessioned2018-03-07T08:11:32Z
dc.date.available2018-03-07T08:11:32Z
dc.date.issued2018-03-07
dc.description.abstractPyrazoline is a five-ring heterocyclic compound with three carbon atoms and two adjacent nitrogen atoms. The presence of electron-rich nitrogen atoms causes these compounds have various biological activities, such as anticancer, antitumor and antioxidant. The pyrazoline (PF-3Br-2OMe) was synthesized by a one-pot three-component reaction between 2-methoxybenzaldehyde, 3-bromoacetophenone and phenylhydrazine with strong base catalyst (NaOH). The synthesis of pyrazoline compound PF-3Br-2OMe was done by comparison of microwave irradiation method, reflux and solvent free. The structure of synthesized compound were confirmed by UV, FTIR, NMR and HRMS spectra. It was concluded that the good method for synthesis of pyrazoline PF-3Br-2OMe in the case of yield was the reflux method, with a yield of 40.51%. While the method was superior in terms of reaction time was microwave irradiation method with reaction time of 1 minute and yield of 34.83%.en_US
dc.description.sponsorshipFakultas Matematika dan Ilmu Pengetahuan Alam Universitas Riauen_US
dc.identifier.otherwahyu sari yeni
dc.identifier.urihttps://repository.unri.ac.id/xmlui/handle/123456789/9276
dc.language.isoenen_US
dc.subjectmicrowave irradiationen_US
dc.subjectone-poten_US
dc.subjectpyrazolineen_US
dc.subjectrefluxen_US
dc.subjectsolvent freeen_US
dc.titlePERBANDINGAN METODE SINTESIS ONE-POT SENYAWA 3-(3-BROMOFENIL)-5-(2-METOKSIFENIL)-1-FENIL-4,5- DIHIDRO-PIRAZOLen_US
dc.typeArticleen_US

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
Jurnal Ilmiah Dini Izzaty.pdf
Size:
2.04 MB
Format:
Adobe Portable Document Format
Description:
artikel
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Chemical